"To get to know, to discover, to publish—this is the destiny of a scientist."
A bipartite structural organization defines the SERINC family of HIV-1 restriction factors
Valerie E. Pye, Annachiara Rosa, Cinzia Bertelli, Weston B. Struwe, Sarah L. Maslen, Robin Corey, Idlir Liko, Mark Hassall, Giada Mattiuzzo, Allison Ballandras-Colas, Andrea Nans, Yasuhiro Takeuchi, Phillip J. Stansfeld, J. Mark Skehel, Carol V. Robinson, Massimo Pizzato & Peter Cherepanov Nature Structural & Molecular Biology, Vol. 27, pages 78-83 (2020)
SERINC5 as a New Restriction Factor for Human Immunodeficiency Virus and Murine Leukemia Virus
Claudia Firrito, Cinzia Bertelli, Teresa Vanzo, Ajit Chande, and Massimo Pizzato
Annual Review of Virology, Vol. 5:323-340 (Volume publication date September 2018)
DOI: 10.1146/annurev-virology-092917-043308 | |
File Size: | 1211 kb |
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SERINC5: not all splice variants work against HIV
Ajit Chande, Claudia Firrito, Massimo Pizzato
Journal of Public Health and Emergency, Vol. 1, No 9 (September 2017)
SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins
Chetan Sood, Mariana Marin, Ajit Chande, Massimo Pizzato and Gregory B. Melikyan
The Journal of Biological Chemistry, 292, 6014-6026 (April 7, 2017)
DOI: 10.1074/jbc.M117.777714 | |
File Size: | 3771 kb |
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S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3
Ajit Chande, Emilia Cristiana Cuccurullo, Annachiara Rosa, Serena Ziglio, Susan Carpenter, Massimo Pizzato
Proceedings of the National Academy of Sciences , 113 (46) 13197-13202 (Nov 2016)
DOI: 10.1073/pnas.1612044113 | |
File Size: | 1224 kb |
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Antagonism of the SERINC5 Particle Infectivity Restriction by HIV-1 Nef Involves Counteraction of Virion-associated Pools of the Restriction Factor
Trautz B, Pierini V, Wombacher R, Stolp B, Chase AJ, Pizzato M, Fackler OT.
Journal of virology. JVI.01246-16 (2016)
doi: 10.1128/JVI.01246-16 | |
File Size: | 2437 kb |
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The Potency of Nef-mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild
Heigele A, Kmiec D, Regensburger K, Langer S, Peiffer L, Stürzel CM, Sauter D, Peeters M, Pizzato M, Learn GH, Hahn B, Kirchhoff F.
Cell Host and Microbe, 20: 381-391 (2016).
DOI: 10.1016/j.chom.2016.08.004 | |
File Size: | 2811 kb |
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SERINC5: a blood cell guardian against HIV
Massimo Pizzato
published on May 13, 2016
Nef promotes infection by excluding SERINC5 from virion incorporation
Annachiara Rosa, Ajit Chande, Serena Ziglio, Veronica De Sanctis, Roberto Bertorelli, Shih Lin Goh, Sean M. McCauley, Anetta Nowosielska, Stylianos
E. Antonarakis, Jeremy Luban, Federico Andrea Santoni & Massimo Pizzato
Nature 526, 212–217 (2015)
DOI: 10.1038/nature15399 | |
File Size: | 5989 kb |
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Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration
Pizzato M, McCauley SM, Neagu MR, Pertel T, Firrito C, Ziglio S, Dauphin A, Zufferey M, Berthoux L & Luban J.
PLoS pathogens 11, e1005050 (2015)
DOI: 10.1371/journal.ppat.1005050 | |
File Size: | 2489 kb |
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TRIM5 is an innate immune sensor for the retrovirus capsid lattice
Pertel T, Hausmann S, Morger D, Zuger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, Grutter MG & Luban J.
Nature 472, 361-365 (2011)
DOI :10.1038/nature09976. | |
File Size: | 1177 kb |
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Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41
Rachel P.J. Lai, Jin Yan, Jonathan Heeney, Myra O. McClure, Heinrich Göttlinger, Jeremy Luban, Massimo Pizzato
PLoS Pathogens (December 15, 2011)
DOI: 10.1371/journal.ppat.1002442 | |
File Size: | 620 kb |
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MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1"
Pizzato M.
PNAS 107, 9364-9369 (2010).
DOI: 10.1073/pnas.1001554107 | |
File Size: | 822 kb |
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A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants.
Pizzato M, Erlwein O, Bonsall D, Kaye S, Muir D, McClure MO.
J Virol Methods. 156(1-2):1-7 (2009)
DOI: 10.1016/j.jviromet.2008.10.012 | |
File Size: | 504 kb |
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Identification of gammaretroviruses constitutively released from cell lines used for human immunodeficiency virus research
Takeuchi Y, McClure MO & Pizzato M.
Journal of virology 82, 12585-12588 (2008).
DOI: 10.1128/JVI.01726-08.pdf | |
File Size: | 217 kb |
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